Oxidative stress and antioxidant status in acute organophosphorous pesticides poisoning cases of North Karnataka
نویسندگان
چکیده
This study was conducted to assess oxidative stress and antioxidant status of organophosphorus (OP) poisoning cases before and after therapy with atropine and pralidoxime of north Karnataka (India). For this study 30 male OP poisoning cases (study group) and 30 male normal healthy subjects (control group) having age range 17-40 years were taken. All organophosphorus poisoning cases were diagnosed by physicians.
منابع مشابه
Relevance of Plasma Cholinesterase to Clinical Findings in Acute Organophosphorous Poisoning
Background: Organophosphorus (OP) poisoning is a major public health problem in developing world. OP pesticides inhibit carboxylic esterase enzymes including plasma cholinesterase (PChE). Clinical manifestations following OP poisoning can be associated with the extent of decrease of PChE. This study was designed to investigate the relevance of PChE level to clinical manifestations in OP poisoni...
متن کاملRecent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning
Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...
متن کاملRecent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning
Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...
متن کاملOxidative stress and antioxidant status in acute organophosphorous insecticide poisoning
Objective: To study the antioxidant status and the extent of oxidative stress in patients with organophosphorus insecticide (OPI) poisoning before and after specific treatment. Material and Methods: The study was conducted in eighty-four OPI poisoned patients. Superoxide dismutase (SOD) and malonyl aldehyde (MDA) levels were estimated as an index of antioxidant status and oxidative stress respe...
متن کاملAcute organo-phosphorus pesticide poisoning in North Karnataka, India: oxidative damage, haemoglobin level and total leukocyte.
BACKGROUND Pesticide poisoning is an important cause of morbidity and mortality in India. OBJECTIVES To assess the oxidative damage, hemoglobin level and leukocyte count in acute organophosphorus pesticide poisoning. METHODS Plasma cholinesterase was assessed as a toxicity marker. Oxidative damage was assessed by estimating serum malondialdehyde (MDA) levels, plasma total antioxidant capaci...
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